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Top startup acquisitions · North America

Top startup acquisitions in North America in April 2026

We tracked 23 startup exits in April 2026, 1 of them acquihires. 6 disclosed a price, worth $11.3bn in total. The biggest was Eli Lilly buying Kelonia Therapeutics for $7bn, ahead of Eli Lilly and Ajax Therapeutics at $2.3bn.

All North America startup acquisitions →
  1. #DateAcquirer → StartupSectorLocationPriceSize
  2. 120 AprEli Lilly → Kelonia TherapeuticsEli Lilly to acquire Kelonia Therapeutics for up to $7 billion in cashHealthtech & bioBoston, United States$7bn$1bn+
  3. 227 AprEli Lilly → Ajax TherapeuticsEli Lilly agrees to buy Ajax Therapeutics for up to $2.3 billionHealthtech & bioNew York, United States$2.3bn$1bn+
  4. 317 AprUCB → Neurona TherapeuticsUCB to acquire epilepsy cell therapy developer Neurona Therapeutics for up to $1.15 billionHealthtech & bioSouth San Francisco, United States$1.15bn$1bn+
  5. 416 AprFoundation Medicine → SAGA DiagnosticsRoche's Foundation Medicine agrees to buy SAGA Diagnostics for up to $595 millionHealthtech & bioResearch Triangle Park, United States$595m$250m–1bn
  6. 514 AprAppDirect → PartnerStackAppDirect acquires Toronto's PartnerStack in a deal reported at over $150 millionEnterprise softwareToronto, Canada$150m$50–250m
  7. 630 AprRecharge → SkioRecharge buys Shopify subscription rival Skio for $105 million in cash, founder saysCommerce & marketingNew York, United States$105m$50–250m
  8. 730 AprPalo Alto Networks → PortkeyPalo Alto Networks agrees to acquire AI gateway startup PortkeyAISan Francisco, United StatesUndisclosedUndisclosed
  9. 829 AprAugment → MerlinAugment acquires stealth startup Merlin to take its AI teammate into wholesale distributionAISan Francisco, United StatesUndisclosedUndisclosed
  10. 928 AprAzra AI → Thynk HealthAzra AI acquires lung cancer screening software maker Thynk HealthHealthtech & bioLexington, United StatesUndisclosedUndisclosed
  11. 1028 AprSocket → Secure AnnexSocket acquires Secure Annex, a one-person startup that watches browser and editor extensionsCybersecurityUnited StatesUndisclosedUndisclosed
  12. 1121 AprOpenTable → LibroOpenTable acquires Montreal restaurant booking platform LibroTravel & hospitalityMontreal, CanadaUndisclosedUndisclosed
  13. 1221 AprProtecht → VISO TRUSTProtecht acquires VISO TRUST, an AI platform for third-party cyber riskCybersecuritySan Francisco, United StatesUndisclosedUndisclosed
  14. 1320 AprCoursedog → ClassRankedCoursedog acquires ClassRanked to add course evaluations to its college softwareEdtechSalt Lake City, United StatesUndisclosedUndisclosed
  15. 1420 AprModMed → Bonsai HealthModMed acquires Bonsai Health, an AI patient outreach startup from the PatientPop foundersHealthtech & bioUnited StatesUndisclosedUndisclosed
  16. 1517 AprMicrosoft → FintoolMicrosoft acquires Fintool, a Y Combinator AI startup for financial researchAISan Francisco, United StatesUndisclosedUndisclosed
  17. 1614 AprSanas → Tomato.aiSanas acquires real-time voice transformation startup Tomato.aiAIUnited StatesUndisclosedUndisclosed
  18. 1713 AprFortreum → Kovr.AIFortreum acquires Kovr.AI, a FedRAMP-authorized AI compliance platformCybersecurityReston, United StatesUndisclosedUndisclosed
  19. 1813 AprOpenAI → HiroOpenAI acquires the team behind Hiro, Ethan Bloch's AI personal finance appFintechUnited StatesUndisclosedUndisclosed
  20. 1910 AprTELCOR → Sample HealthcareTELCOR acquires Y Combinator-backed Sample Healthcare to automate lab billing work with AIHealthtech & bioUnited StatesUndisclosedUndisclosed
  21. 209 AprCisco → GalileoCisco to acquire Galileo, the AI agent evaluation and observability startup, for SplunkAISan Francisco, United StatesUndisclosedUndisclosed
  22. 219 AprGusto → MoseyGusto acquires Mosey to add state and local compliance for small businessesHR & workUnited StatesUndisclosedUndisclosed
  23. 229 AprMotorola Solutions → HyperMotorola Solutions acquires Hyper, a startup whose AI agents answer non-emergency 911 callsAIToronto, CanadaUndisclosedUndisclosed
  24. 237 AprCENTEGIX → PikmykidCENTEGIX acquires Tampa school dismissal and safety platform PikmykidEdtechTampa, United StatesUndisclosedUndisclosed